When chemist Rafael Mechoulam did his first research on cannabis in the early 60s, he was faced with a big problem: Where to find legal marijuana for scientific research. ?
While hardly a single vendor is suitable in today’s legal and political climate, the 5 kg Mechoulam hashish obtained by the Israeli police helped pave the way for some of the ground-breaking discoveries. in cannabis and biochemical research to date.
Watching: What is Thc?
(At the beginning of his cannabis research, Mechoulam bought marijuana from the Israeli police. He then followed the rules and asked to use marijuana legally under the strict management of the Israeli government. ).
Mechoulam was the first to isolate delta9-tetrahydrocannabinol (THC), the essential oil responsible for the high effect in the cannabis plant.
What is Delta9-Tetrahydrocannabinol?
THC is one of the chemical compounds known as phyto-cannabinoids found inside the resinous glands mainly in the buds or flowers of the female cannabis plant.
In organic chemistry, phyto-cannabinoids act as secondary metabolites or supplements, are produced by the cannabis plant and do not have a direct effect on plant growth or reproduction.
The cannabis plant produces secondary metabolites in the internal immune system that fight off parasites, viruses, bacteria and other natural predators. While THC by itself has no anti-bacterial properties in humans, other phyto-cannabinoids such as cannabigerol (CBG) are known to kill or slow the growth of bacteria in humans and plants. the same, similar.
A scientific look at THC.
With that said, THC is the only psychoactive compound in the cannabis plant. So why is the attention turning to cannabidiol (CBD)?
CBD is the 2nd most common cannabinoid in cannabis, but unlike THC, it does not bind to any specific cannabinoid receptor in the body and is not psychoactive.
CBD works by inhibiting the enzyme that catalyzes the hydrolysis of fatty acids (Fatty Acid Amide Hydrolase/FAAH), which breaks down Anandamide in the body. This increases the amount of Anandamide present in the body because the FAAH enzyme is no longer able to destroy Anandamide.
CBD is known by biochemists as an antagonist to THC. Simply put, CBD makes some of the effects of THC not happen.
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CBD may have a very low binding force on the CB1 receptor in the CNS, but the compound can still act on the receptors. And so, CBD dominates and blocks other connections to the brain’s CB1 receptors, rendering THC unworkable.
While THC stimulates the appetite, CBD has the opposite effect making it quite similar to the controversial weight loss drug Rimonabant. Since CBD is not a psychedelic ingredient, it cannot give a high feeling. like THC is. Research shows that CBD has analgesic, anti-inflammatory, and anti-anxiety effects. CBD has antipsychotic properties. It can protect the user from getting too high by reducing the shikigami effects of THC. CBD is also being tested in the treatment of schizophrenia. THC can cause restlessness, anxiety and paranoia. In contrast, CBD works to counteract the effects caused by THC, while also working on its own to reduce anxiety. THC is responsible for most marijuana for its sedating effects. . CBD does not, it helps increase alertness. This opposite effect may explain why some strains of cannabis cause drowsiness while others increase energy.
Medicinal value of THC.
While cannabis continues to be accepted in many mainstream cultures, more and more research is being conducted and bringing the medicinal value of THC to light. Most notably, the discovery of THC’s potential in cancer treatment.
Researchers from the Compultense University in Madrid have discovered that THC can actually induce tumor cells to self-destruct in animal models, meaning that THC plays a key role in the powerful reduce tumor size and metastasis.
THC is also used by pharmaceutical companies to make drugs such as Marinol, which is a drug prescribed to stimulate appetite and reduce nausea in cancer patients.
Every year, more studies show the effectiveness of THC in medicine. Up to this point, THC is considered as an effective helper in the treatment of the following diseases:
Alzheimer’s (a memory loss common in older people)Atherosclerosis Neuropathy (Neuropathic pain) Multiple sclerosis (a disorder of the brain and spinal cord) – Multiple sclerosisParkinson (degeneration of the central nervous system) – Parkinson’s Disease Sleep breathing disorder (apnea) – Sleep apnea Attention-deficit/hyperactivity disorder/ADHD (dysfunction – hyperactivity and inability to concentrate) Tourette’s syndrome (disorder of the central nervous system, usually beginning around 2 up to age 21 and lasting for life)Post Traumatic Stress Disorder/PTSDU Cancer (various types)
Formulas that use THC.
All this information about THC should have given you a healthier perspective on marijuana. Here are some recipes that include THC extract that you can refer to:
Cannabis oil THC as a compress Cannabis (coconut) oil Cannabis honey tincture
When it comes to THC, the research summarized in this article is just the tip of the iceberg. Through THC research to date, scientists like Rafael Mechoulam and Allyn Howlett have opened our eyes to a complex biochemical system that humans are just beginning to understand.
While THC shows great potential as a drug and as a tool to help people understand the complex ways in which substances in the body affect psychology, legalization and key barriers Politics is still preventing us from fully investigating what the cannabis plant can teach us about ourselves.
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