APC . gene testing

This blood test can find a variant of the APC gene that makes some people more likely to develop FAP (familial adenomatous polyposis).

Viewing: What is Apc

4.1 Situations where genetic testing is recommended:

More than 10 colon polypsColon polyps and other types of tumorsYou are of Ashkenazi Jewish descent. Your family has a history of colon cancer or polyps can become cancerous.

4.2 Meaning of the test

APC variant genetic testing does not check if you have cancer or polyps. It only looks for a specific variant in the APC gene that could put you at risk. The doctor may refer to the test result as “positive” or “negative”. Those words mean something different than you think.

4.3 “positive” test result

It means you have a malfunctioning APC gene. That makes you more likely to get FAP than people who don’t. But that doesn’t mean you’ll definitely get it. If you already have colon cancer or polyps, it can affect how often you need to be checked.

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4.4 “negative” result

Meaning you don’t have that gene variant. Remember that the test does not check for every possible problem with this gene. This trial also did not look at other genetic problems that run in families with colon cancer. It only looks for the APC gene variant.

4.5 What to do if the result is “positive”

?If it is found that you have the APC gene variant, your doctor will likely recommend an annual colonoscopy. This is a test that allows your doctor to examine your intestines for cancer or polyps that may become cancerous.

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If you’ve had colon cancer or polyps before, your doctor may recommend removal.

As we all know, the APC gene participates in many signaling and cell attachment processes in the body. Mutations in the APC gene cause disturbances in the synthesis of APC proteins. It is the cause of many health problems, especially colorectal cancer. Testing for the APC gene can help us detect genetic changes that can cause this cancerous condition.